p53-dependent elimination of aneuploid mitotic offspring by entosis

Entosis was proposed to promote aneuploidy and genome instability by cell-in-cell mediated engulfment in tumor cells. We reported here, in epithelial cells, that entosis coupled with mitotic arrest functions to counteract genome instability by targeting aneuploid mitotic progenies for engulfment and...

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Gepubliceerd in:Cell Death Differ
Hoofdauteurs: Liang, Jianqing, Niu, Zubiao, Zhang, Bo, Yu, Xiaochen, Zheng, You, Wang, Chenxi, Ren, He, Wang, Manna, Ruan, Banzhan, Qin, Hongquan, Zhang, Xin, Gu, Songzhi, Sai, Xiaoyong, Tai, Yanhong, Gao, Lihua, Ma, Li, Chen, Zhaolie, Huang, Hongyan, Wang, Xiaoning, Sun, Qiang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862607/
https://ncbi.nlm.nih.gov/pubmed/33110215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00645-3
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