p53-dependent elimination of aneuploid mitotic offspring by entosis

Entosis was proposed to promote aneuploidy and genome instability by cell-in-cell mediated engulfment in tumor cells. We reported here, in epithelial cells, that entosis coupled with mitotic arrest functions to counteract genome instability by targeting aneuploid mitotic progenies for engulfment and...

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Publicat a:Cell Death Differ
Autors principals: Liang, Jianqing, Niu, Zubiao, Zhang, Bo, Yu, Xiaochen, Zheng, You, Wang, Chenxi, Ren, He, Wang, Manna, Ruan, Banzhan, Qin, Hongquan, Zhang, Xin, Gu, Songzhi, Sai, Xiaoyong, Tai, Yanhong, Gao, Lihua, Ma, Li, Chen, Zhaolie, Huang, Hongyan, Wang, Xiaoning, Sun, Qiang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862607/
https://ncbi.nlm.nih.gov/pubmed/33110215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-00645-3
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