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Immune Responses to Plasma-Derived Versus Recombinant FVIII Products

The most severe side effect of hemophilia treatment is the inhibitor development occurring in 30% of patients, during the earliest stages of treatment with factor (F)VIII concentrates. These catastrophic immune responses rapidly inactivate the infused FVIII, rendering the treatment ineffective. This...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Peyvandi, Flora, Miri, Syna, Garagiola, Isabella
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862552/
https://ncbi.nlm.nih.gov/pubmed/33552050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.591878
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