Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation

Pancreatic ductal adenocarcinoma (PDAC) has poor prognosis due to limited therapeutic options. This study examines the roles of genome-wide association study identified PDAC-associated genes as therapeutic targets. We have identified HNF4G gene whose silencing most effectively repressed PDAC cell in...

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Gepubliceerd in:Protein Cell
Hoofdauteurs: Wang, Chengcheng, Zhang, Taiping, Liao, Quan, Dai, Menghua, Guo, Junchao, Yang, Xinyu, Tan, Wen, Lin, Dongxin, Wu, Chen, Zhao, Yupei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Higher Education Press 2020
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862466/
https://ncbi.nlm.nih.gov/pubmed/32737864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-020-00760-4
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