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SPT6 promotes epidermal differentiation and blockade of an intestinal-like phenotype through control of transcriptional elongation

In adult tissue, stem and progenitor cells must tightly regulate the balance between proliferation and differentiation to sustain homeostasis. How this exquisite balance is achieved is an area of active investigation. Here, we show that epidermal genes, including ~30% of induced differentiation gene...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Nat Commun
Main Authors: Li, Jingting, Xu, Xiaojun, Tiwari, Manisha, Chen, Yifang, Fuller, Mackenzie, Bansal, Varun, Tamayo, Pablo, Das, Soumita, Ghosh, Pradipta, Sen, George L.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862286/
https://ncbi.nlm.nih.gov/pubmed/33542242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21067-w
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