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DNA-launched RNA replicon vaccines induce potent anti-SARS-CoV-2 immune responses in mice

The outbreak of the SARS-CoV-2 virus and its rapid spread into a global pandemic made the urgent development of scalable vaccines to prevent coronavirus disease (COVID-19) a global health and economic imperative. Here, we characterized and compared the immunogenicity of two alphavirus-based DNA-laun...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Szurgot, Inga, Hanke, Leo, Sheward, Daniel J., Vidakovics, Laura Perez, Murrell, Ben, McInerney, Gerald M., Liljeström, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7862230/
https://ncbi.nlm.nih.gov/pubmed/33542325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82498-5
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