Adjuvanted SARS-CoV-2 spike protein elicits neutralizing antibodies and CD4 T cell responses after a single immunization in mice

BACKGROUND: SARS-CoV-2 has caused a global pandemic, infecting millions of people. A safe, effective vaccine is urgently needed and remains a global health priority. Subunit vaccines are used successfully against other viruses when administered in the presence of an effective adjuvant. METHODS: We e...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Wørzner, Katharina, Sheward, Daniel J., Schmidt, Signe Tandrup, Hanke, Leo, Zimmermann, Julie, McInerney, Gerald, Hedestam, Gunilla B. Karlsson, Murrell, Ben, Christensen, Dennis, Pedersen, Gabriel Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7808923/
https://ncbi.nlm.nih.gov/pubmed/33422991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103197
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