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SuperGAG biopolymers for treatment of excessive bladder permeability

Few therapeutic options exist for treatment of IC/BPS. A novel high MW GAG biopolymer (“SuperGAG”) was synthesized by controlled oligomerization of CS, purified by TFF and characterized by SEC‐MALLS and 1H‐NMR spectroscopy. The modified GAG biopolymer was tested in an OVX female rat model in which b...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Towner, Rheal A., Greenwood‐Van Meerveld, Beverley, Mohammadi, Ehsan, Saunders, Debra, Smith, Nataliya, Sant, Grannum R., Shain, Harrison C., Jozefiak, Thomas H., Hurst, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7861891/
https://ncbi.nlm.nih.gov/pubmed/33540486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.709
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