In vivo and ex vivo assessment of bladder hyper-permeability and using molecular targeted magnetic resonance imaging to detect claudin-2 in a mouse model for interstitial cystitis

OBJECTIVES: To determine if the URO-MCP-1 mouse model for bladder IC/BPS is associated with in vivo bladder hyper-permeability, as measured by contrast-enhanced MRI (CE-MRI), and assess whether molecular-targeted MRI (mt-MRI) can visualize in vivo claudin-2 expression as a result of bladder hyper-pe...

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Publicado en:PLoS One
Main Authors: Smith, Nataliya, Saunders, Debra, Lerner, Megan, Zalles, Michelle, Mamedova, Nadezda, Cheong, Daniel, Mohammadi, Ehsan, Yuan, Tian, Luo, Yi, Hurst, Robert E., Greenwood-Van Meerveld, Beverley, Towner, Rheal A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7584247/
https://ncbi.nlm.nih.gov/pubmed/33095778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239282
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