Polygenic risk score validation using Korean genomes of 265 early-onset acute myocardial infarction patients and 636 healthy controls

BACKGROUND: The polygenic risk score (PRS) developed for coronary artery disease (CAD) is known to be effective for classifying patients with CAD and predicting subsequent events. However, the PRS was developed mainly based on the analysis of Caucasian genomes and has not been validated for East Asi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Bhak, Youngjune, Jeon, Yeonsu, Jeon, Sungwon, Yoon, Changhan, Kim, Min, Blazyte, Asta, Kim, Yeonkyung, Kang, Younghui, Kim, Changjae, Lee, Sang Yeub, Bae, Jang-Whan, Kim, Weon, Kim, Yeo Jin, Shim, Jungae, Kim, Nayeong, Chun, Sung, Kim, Byoung-Chul, Kim, Byung Chul, Lee, Semin, Bhak, Jong, Shin, Eun-Seok
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2021
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7861392/
https://ncbi.nlm.nih.gov/pubmed/33539413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0246538
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