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Sensitivity-specificity of tau and Aβ PET in frontotemporal lobar degeneration

OBJECTIVE: To examine associations between tau and amyloid-beta (Aβ) molecular PET and both Alzheimer-related pathology and 4-repeat tau pathology in autopsy-confirmed frontotemporal lobar degeneration (FTLD). METHODS: Twenty-four patients had [(18)F]-Flortaucipir PET and died with FTLD (progressive...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Ghirelli, Alma, Tosakulwong, Nirubol, Weigand, Stephen D., Clark, Heather M., Ali, Farwa, Botha, Hugo, Duffy, Joseph R., Utianski, Rene L., Buciuc, Marina, Murray, Melissa E., Labuzan, Sydney A., Spychalla, Anthony J., Pham, Nha Trang Thu, Schwarz, Christopher G., Senjem, Matthew L., Machulda, Mary M., Baker, Matthew, Rademakers, Rosa, Filippi, Massimo, Jack, Clifford R., Lowe, Val J., Parisi, Joseph E, Dickson, Dennis W., Josephs, Keith A., Whitwell, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7861121/
https://ncbi.nlm.nih.gov/pubmed/32869362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25893
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