Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation

Primitive neuroectodermal tumors of the central nervous system (CNS-PNETs) are highly malignant neoplasms posing diagnostic challenge due to a lack of defining molecular markers. CNS neuroblastoma with forkhead box R2 (FOXR2) activation (CNS_NBL) emerged as a distinct pediatric brain tumor entity fr...

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Sparad:
Bibliografiska uppgifter
I publikationen:Acta Neuropathol Commun
Huvudupphovsmän: Korshunov, Andrey, Okonechnikov, Konstantin, Schmitt-Hoffner, Felix, Ryzhova, Marina, Sahm, Felix, Stichel, Damian, Schrimpf, Daniel, Reuss, David E., Sievers, Philipp, Suwala, Abigail Kora, Kumirova, Ella, Zheludkova, Olga, Golanov, Andrey, Jones, David T. W., Pfister, Stefan M., Kool, Marcel, von Deimling, Andreas
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2021
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860633/
https://ncbi.nlm.nih.gov/pubmed/33536079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-021-01118-5
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