DNA methylation profiling is a method of choice for molecular verification of pediatric WNT-activated medulloblastomas

BACKGROUND: Wingless-activated medulloblastoma (WNT MB) represents a well-characterized molecular variant accounting for 10–15% of all MB and is associated with a favorable clinical outcome. Patients with localized WNT MBs could benefit from de-intensification of combined treatment, which would requ...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Korshunov, Andrey, Sahm, Felix, Zheludkova, Olga, Golanov, Andrey, Stichel, Damian, Schrimpf, Daniel, Ryzhova, Marina, Potapov, Alexander, Habel, Antje, Meyer, Jochen, Lichter, Peter, Jones, David T W, von Deimling, Andreas, Pfister, Stefan M, Kool, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6374763/
https://ncbi.nlm.nih.gov/pubmed/30252101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy155
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