Reelin Depletion Protects Against Autoimmune Encephalomyelitis by Decreasing Vascular Adhesion of Leukocytes

Neuroinflammation as a result of immune cell recruitment into the central nervous system (CNS) is a key pathogenic mechanism of multiple sclerosis (MS). However, current anti-inflammatory interventions depleting immune cells or directly targeting their trafficking into the CNS can have serious side...

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Vydáno v:Sci Transl Med
Hlavní autoři: Calvier, Laurent, Demuth, Guillaume, Manouchehri, Navid, Wong, Connie, Sacharidou, Anastasia, Mineo, Chieko, Shaul, Philip W., Monson, Nancy L, Kounnas, Maria Z, Stüve, Olaf, Herz, Joachim
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860587/
https://ncbi.nlm.nih.gov/pubmed/32801146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aay7675
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