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3 (′)-5 (′) crosstalk contributes to transcriptional bursting

BACKGROUND: Transcription in mammalian cells is a complex stochastic process involving shuttling of polymerase between genes and phase-separated liquid condensates. It occurs in bursts, which results in vastly different numbers of an mRNA species in isogenic cell populations. Several factors contrib...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Cavallaro, Massimo, Walsh, Mark D., Jones, Matt, Teahan, James, Tiberi, Simone, Finkenstädt, Bärbel, Hebenstreit, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860045/
https://ncbi.nlm.nih.gov/pubmed/33541397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02227-5
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