GLI2 but not GLI1/GLI3 plays a central role in the induction of malignant phenotype of gallbladder cancer

We previously reported that Hedgehog (Hh) signal was enhanced in gallbladder cancer (GBC) and was involved in the induction of malignant phenotype of GBC. In recent years, therapeutics that target Hh signaling have focused on molecules downstream of smoothened (SMO). The three transcription factors...

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Publicat a:Oncol Rep
Autors principals: Ichimiya, Shu, Onishi, Hideya, Nagao, Shinjiro, Koga, Satoko, Sakihama, Kukiko, Nakayama, Kazunori, Fujimura, Akiko, Oyama, Yasuhiro, Imaizumi, Akira, Oda, Yoshinao, Nakamura, Masafumi
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2021
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7860001/
https://ncbi.nlm.nih.gov/pubmed/33650666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2021.7947
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