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rHDL modeling and the anchoring mechanism of LCAT activation

Lecithin:cholesterol-acyl transferase (LCAT) plays a major role in cholesterol metabolism as it is the only extracellular enzyme able to esterify cholesterol. LCAT activity is required for lipoprotein remodeling and, most specifically, for the growth and maturation of HDLs. In fact, genetic alterati...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Laurenzi, Tommaso, Parravicini, Chiara, Palazzolo, Luca, Guerrini, Uliano, Gianazza, Elisabetta, Calabresi, Laura, Eberini, Ivano
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859856/
https://ncbi.nlm.nih.gov/pubmed/33518511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000843
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