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rHDL modeling and the anchoring mechanism of LCAT activation

Lecithin:cholesterol-acyl transferase (LCAT) plays a major role in cholesterol metabolism as it is the only extracellular enzyme able to esterify cholesterol. LCAT activity is required for lipoprotein remodeling and, most specifically, for the growth and maturation of HDLs. In fact, genetic alterati...

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Detalles Bibliográficos
Publicado en:J Lipid Res
Autores principales: Laurenzi, Tommaso, Parravicini, Chiara, Palazzolo, Luca, Guerrini, Uliano, Gianazza, Elisabetta, Calabresi, Laura, Eberini, Ivano
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859856/
https://ncbi.nlm.nih.gov/pubmed/33518511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA120000843
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