In silico Description of LAT1 Transport Mechanism at an Atomistic Level

The molecular mechanism of transport mediated by LAT1, a sodium-independent antiporter of large neutral amino acids, was investigated through in silico procedures, specifically making reference to two transported substrates, tyrosine (Tyr) and leucine methyl ester (LME), and to 3,5-diiodo-L-tyrosine...

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Detalles Bibliográficos
Publicado en:Front Chem
Main Authors: Palazzolo, Luca, Parravicini, Chiara, Laurenzi, Tommaso, Guerrini, Uliano, Indiveri, Cesare, Gianazza, Elisabetta, Eberini, Ivano
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Chemistry
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117385/
https://ncbi.nlm.nih.gov/pubmed/30197880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00350
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