The melibiose-derived glycation product mimics a unique epitope present in human and animal tissues

Non-enzymatic modification of proteins by carbohydrates, known as glycation, leads to generation of advanced glycation end-products (AGEs). In our study we used in vitro generated AGEs to model glycation in vivo. We discovered in vivo analogs of unusual melibiose-adducts designated MAGEs (mel-derive...

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Publicado no:Sci Rep
Main Authors: Staniszewska, Magdalena, Bronowicka-Szydełko, Agnieszka, Gostomska-Pampuch, Kinga, Szkudlarek, Jerzy, Bartyś, Arkadiusz, Bieg, Tadeusz, Gamian, Elżbieta, Kochman, Agata, Picur, Bolesław, Pietkiewicz, Jadwiga, Kuropka, Piotr, Szeja, Wiesław, Wiśniewski, Jerzy, Ziółkowski, Piotr, Gamian, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7859244/
https://ncbi.nlm.nih.gov/pubmed/33536563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82585-7
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