Dietary Indole-3-Carbinol Activates AhR in the Gut, Alters Th17-Microbe Interactions, and Exacerbates Insulitis in NOD Mice

The diet represents one environmental risk factor controlling the progression of type 1 diabetes (T1D) in genetically susceptible individuals. Consequently, understanding which specific nutritional components promote or prevent the development of disease could be used to make dietary recommendations...

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Publicado en:Front Immunol
Autores principales: Kahalehili, Heather M., Newman, Nolan K., Pennington, Jamie M., Kolluri, Siva K., Kerkvliet, Nancy I., Shulzhenko, Natalia, Morgun, Andrey, Ehrlich, Allison K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7858653/
https://ncbi.nlm.nih.gov/pubmed/33552063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.606441
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