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Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP)

The Plasmodium falciparum M1 alanyl aminopeptidase and M17 leucyl aminopeptidase, PfM1AAP and PfM17LAP, are potential targets for novel anti-malarial drug development. Inhibitors of these aminopeptidases have been shown to kill malaria parasites in culture and reduce parasite growth in murine models...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Mathew, Rency, Wunderlich, Juliane, Thivierge, Karine, Cwiklinski, Krystyna, Dumont, Claire, Tilley, Leann, Rohrbach, Petra, Dalton, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7858622/
https://ncbi.nlm.nih.gov/pubmed/33536500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-82499-4
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