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Alpha-1 Antitrypsin Deficiency: Have We Got the Right Proteinase?

Alpha-1 antitrypsin deficiency (AATD) has traditionally been associated with the development of early onset panlobular emphysema thought to reflect the direct interstitial damage caused by neutrophil elastase. Since this enzyme is highly sensitive to irreversible inhibition by alpha-1 antitrypsin (A...

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Dettagli Bibliografici
Pubblicato in:Chronic Obstr Pulm Dis
Autore principale: Stockley, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: COPD Foundation Inc 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857712/
https://ncbi.nlm.nih.gov/pubmed/32396717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15326/jcopdf.7.3.2019.0151
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