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Monocytes and Macrophages in Alpha-1 Antitrypsin Deficiency
Alpha-1 antitrypsin deficiency (AATD) is a genetic condition characterised by low circulating levels of alpha-1 antitrypsin (AAT), a serine proteinase inhibitor. The most common deficiency variants are the S and Z mutations, which cause the accumulation of misfolded AAT in hepatocytes resulting in e...
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| Publié dans: | Int J Chron Obstruct Pulmon Dis |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Dove
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7725100/ https://ncbi.nlm.nih.gov/pubmed/33311976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S276792 |
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