The rs361525 polymorphism does not increase production of tumor necrosis factor alpha by monocytes from alpha-1 antitrypsin deficient subjects with chronic obstructive pulmonary disease - a pilot study

BACKGROUND: Polymorphisms in the TNF-A gene have been associated with chronic obstructive pulmonary disease (COPD) in some case-control studies. Previous work has shown that COPD/chronic bronchitis subjects with alpha-1 antitrypsin deficiency with the rs361525 TNF-α single nucleotide polymorphism ha...

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Publicado en:J Negat Results Biomed
Autores principales: Gane, Jennie M., Stockley, Robert A., Sapey, Elizabeth
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Brief Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665865/
https://ncbi.nlm.nih.gov/pubmed/26620975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12952-015-0039-3
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