USP22 controls necroptosis by regulating receptor‐interacting protein kinase 3 ubiquitination

Dynamic control of ubiquitination by deubiquitinating enzymes is essential for almost all biological processes. Ubiquitin‐specific peptidase 22 (USP22) is part of the SAGA complex and catalyzes the removal of mono‐ubiquitination from histones H2A and H2B, thereby regulating gene transcription. Howev...

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Bibliographic Details
Published in:EMBO Rep
Main Authors: Roedig, Jens, Kowald, Lisa, Juretschke, Thomas, Karlowitz, Rebekka, Ahangarian Abhari, Behnaz, Roedig, Heiko, Fulda, Simone, Beli, Petra, van Wijk, Sjoerd JL
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857539/
https://ncbi.nlm.nih.gov/pubmed/33369872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050163
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