USP22 controls necroptosis by regulating receptor‐interacting protein kinase 3 ubiquitination

Dynamic control of ubiquitination by deubiquitinating enzymes is essential for almost all biological processes. Ubiquitin‐specific peptidase 22 (USP22) is part of the SAGA complex and catalyzes the removal of mono‐ubiquitination from histones H2A and H2B, thereby regulating gene transcription. Howev...

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Udgivet i:EMBO Rep
Main Authors: Roedig, Jens, Kowald, Lisa, Juretschke, Thomas, Karlowitz, Rebekka, Ahangarian Abhari, Behnaz, Roedig, Heiko, Fulda, Simone, Beli, Petra, van Wijk, Sjoerd JL
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857539/
https://ncbi.nlm.nih.gov/pubmed/33369872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050163
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