Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

Zoonotic introduction of novel coronaviruses may encounter preexisting immunity in humans. Using diverse assays for antibodies recognizing SARS-CoV-2 proteins, we detected preexisting humoral immunity. SARS-CoV-2 spike glycoprotein (S)–reactive antibodies were detectable using a flow cytometry–based...

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Vydáno v:Science
Hlavní autoři: Ng, Kevin W., Faulkner, Nikhil, Cornish, Georgina H., Rosa, Annachiara, Harvey, Ruth, Hussain, Saira, Ulferts, Rachel, Earl, Christopher, Wrobel, Antoni G., Benton, Donald J., Roustan, Chloe, Bolland, William, Thompson, Rachael, Agua-Doce, Ana, Hobson, Philip, Heaney, Judith, Rickman, Hannah, Paraskevopoulou, Stavroula, Houlihan, Catherine F., Thomson, Kirsty, Sanchez, Emilie, Shin, Gee Yen, Spyer, Moira J., Joshi, Dhira, O’Reilly, Nicola, Walker, Philip A., Kjaer, Svend, Riddell, Andrew, Moore, Catherine, Jebson, Bethany R., Wilkinson, Meredyth, Marshall, Lucy R., Rosser, Elizabeth C., Radziszewska, Anna, Peckham, Hannah, Ciurtin, Coziana, Wedderburn, Lucy R., Beale, Rupert, Swanton, Charles, Gandhi, Sonia, Stockinger, Brigitta, McCauley, John, Gamblin, Steve J., McCoy, Laura E., Cherepanov, Peter, Nastouli, Eleni, Kassiotis, George
Médium: Artigo
Jazyk:Inglês
Vydáno: American Association for the Advancement of Science 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857411/
https://ncbi.nlm.nih.gov/pubmed/33159009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abe1107
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