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Macrophage Depletion in CCR2(−/−) Mice Delays Bacterial Clearance and Enhances Neutrophil Infiltration in an Acute Otitis Media Model

BACKGROUND: Otitis media (OM) is a common and potentially serious disease of childhood. Although OM is multifactorial on origin, bacterial infection is a unifying component. Many studies have established a critical role for innate immunity in bacterial clearance and OM resolution. A key component of...

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發表在:J Infect Dis
Main Authors: Hur, Dong Gu, Kurabi, Arwa, Lim, Hyun Woo, Spriggs, Meghan, Pak, Kwang, Ryan, Allen F
格式: Artigo
語言:Inglês
出版: Oxford University Press 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857354/
https://ncbi.nlm.nih.gov/pubmed/32572481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiaa353
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