SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO

Coronavirus disease 2019 (COVID-19) is a current global health threat caused by the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Emerging evidence indicates that SARS-CoV-2 elicits a dysregulated immune response and a delayed interferon (IFN) expression in patients...

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Publicado en:Cell Rep
Autores principales: Wu, Jing, Shi, Yuheng, Pan, Xiaoyan, Wu, Shuang, Hou, Ruixia, Zhang, Yong, Zhong, Tiansheng, Tang, Hao, Du, Wei, Wang, Luying, Wo, Jing, Mu, Jingfang, Qiu, Yang, Yang, Ke, Zhang, Lei-Ke, Ye, Bang-Ce, Qi, Nan
Formato: Artigo
Lenguaje:Inglês
Publicado: The Author(s). 2021
Materias:
Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7857071/
https://ncbi.nlm.nih.gov/pubmed/33567255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.108761
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