TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity

Human aging is frequently accompanied by the acquisition of somatic mutations in the hematopoietic system that induce clonal hematopoiesis, leading to the development of a mutant clone of hematopoietic progenitors and leukocytes. This somatic-mutation-driven clonal hematopoiesis has been associated...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Fuster, José J., Zuriaga, María A., Zorita, Virginia, MacLauchlan, Susan, Polackal, Maya N., Viana-Huete, Vanesa, Ferrer-Pérez, Alba, Matesanz, Nuria, Herrero-Cervera, Andrea, Sano, Soichi, Cooper, Matthew A., González-Navarro, Herminia, Walsh, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856871/
https://ncbi.nlm.nih.gov/pubmed/33113366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108326
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