Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction

Clonal hematopoiesis of indeterminate potential is prevalent in elderly individuals and associated with increased risks of all-cause mortality and cardiovascular disease. However, mouse models to study the dynamics of clonal hematopoiesis and its consequences on the cardiovascular system under homeo...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Wang, Ying, Sano, Soichi, Yura, Yoshimitsu, Ke, Zhonghe, Sano, Miho, Oshima, Kosei, Ogawa, Hayato, Horitani, Keita, Min, Kyung-Duk, Miura-Yura, Emiri, Kour, Anupreet, Evans, Megan A., Zuriaga, Maria A., Hirschi, Karen K., Fuster, Jose J., Pietras, Eric M., Walsh, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7213793/
https://ncbi.nlm.nih.gov/pubmed/32154790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135204
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