JAK2(V617F)-Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure

Janus kinase 2 (valine to phenylalanine at residue 617) (JAK2(V617F)) mutations lead to myeloproliferative neoplasms associated with elevated myeloid, erythroid, and megakaryocytic cells. Alternatively these same mutations can lead to the condition of clonal hematopoiesis with no impact on blood cel...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:JACC Basic Transl Sci
Main Authors: Sano, Soichi, Wang, Ying, Yura, Yoshimitsu, Sano, Miho, Oshima, Kosei, Yang, Yue, Katanasaka, Yasufumi, Min, Kyung-Duk, Matsuura, Shinobu, Ravid, Katya, Mohi, Golam, Walsh, Kenneth
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
PRECLINICAL RESEARCH
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834960/
https://ncbi.nlm.nih.gov/pubmed/31709318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.05.013
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