JAK2(V617F)-Mediated Clonal Hematopoiesis Accelerates Pathological Remodeling in Murine Heart Failure

Janus kinase 2 (valine to phenylalanine at residue 617) (JAK2(V617F)) mutations lead to myeloproliferative neoplasms associated with elevated myeloid, erythroid, and megakaryocytic cells. Alternatively these same mutations can lead to the condition of clonal hematopoiesis with no impact on blood cel...

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Detalhes bibliográficos
Publicado no:JACC Basic Transl Sci
Main Authors: Sano, Soichi, Wang, Ying, Yura, Yoshimitsu, Sano, Miho, Oshima, Kosei, Yang, Yue, Katanasaka, Yasufumi, Min, Kyung-Duk, Matsuura, Shinobu, Ravid, Katya, Mohi, Golam, Walsh, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
PRECLINICAL RESEARCH
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6834960/
https://ncbi.nlm.nih.gov/pubmed/31709318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.05.013
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