Helicobacter pylori-induced gastric cancer is orchestrated by MRCKβ-mediated Siah2 phosphorylation

BACKGROUND: Helicobacter pylori-mediated gastric carcinogenesis is initiated by a plethora of signaling events in the infected gastric epithelial cells (GECs). The E3 ubiquitin ligase seven in absentia homolog 2 (Siah2) is induced in GECs in response to H. pylori infection. Posttranslational modific...

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Udgivet i:J Biomed Sci
Main Authors: Dixit, Pragyesh, Kokate, Shrikant B., Poirah, Indrajit, Chakraborty, Debashish, Smoot, Duane T., Ashktorab, Hassan, Rout, Niranjan, Singh, Shivaram P., Bhattacharyya, Asima
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856738/
https://ncbi.nlm.nih.gov/pubmed/33536006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-021-00710-0
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