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Regulation of Noxa-mediated apoptosis in Helicobacter pylori–infected gastric epithelial cells

Helicobacter pylori induces the antiapoptotic protein myeloid cell leukemia 1 (Mcl1) in human gastric epithelial cells (GECs). Apoptosis of oncogenic protein Mcl1-expressing cells is mainly regulated by Noxa-mediated degradation of Mcl1. We wanted to elucidate the status of Noxa in H. pylori–infecte...

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Veröffentlicht in:FASEB J
Hauptverfasser: Rath, Suvasmita, Das, Lopamudra, Kokate, Shrikant Babanrao, Pratheek, B. M., Chattopadhyay, Subhasis, Goswami, Chandan, Chattopadhyay, Ranajoy, Crowe, Sheila Eileen, Bhattacharyya, Asima
Format: Artigo
Sprache:Inglês
Veröffentlicht: Federation of American Societies for Experimental Biology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4422360/
https://ncbi.nlm.nih.gov/pubmed/25404713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-257501
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