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Targeting GPCR Signaling for Idiopathic Pulmonary Fibrosis Therapies
A variety of G-protein coupled receptors (GPCRs) have been implicated in the pathogenesis of pulmonary fibrosis, largely through their promotion of profibrotic fibroblast activation. In contrast, recent work has highlighted the beneficial effects Gαs-coupled GPCRs exert on reducing fibroblast activa...
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| Veröffentlicht in: | Trends Pharmacol Sci |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7856568/ https://ncbi.nlm.nih.gov/pubmed/32008852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2019.12.008 |
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