IL-4-BATF signaling directly modulates IL-9 producing mucosal mast cell (MMC9) function in experimental food allergy

BACKGROUND: We have previously identified IL-9 producing mucosal mast cell (MMC9) as the primary source of IL-9 to drive intestinal mastocytosis and experimental IgE-mediated food allergy. However, the molecular mechanisms that regulate the expansion of MMC9s remain unknown. OBJECTIVE: We hypothesiz...

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Udgivet i:J Allergy Clin Immunol
Main Authors: Tomar, Sunil, Ganesan, Varsha, Sharma, Ankit, Zeng, Chang, Waggoner, Lisa, Smith, Andrew, Kim, Chang H., Licona-Limón, Paula, Reinhardt, Richard L., Flavell, Richard A., Wang, Yui-Hsi, Hogan, Simon P.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856198/
https://ncbi.nlm.nih.gov/pubmed/33069715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.08.043
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