Brain pathology caused in the neonatal macaque by short and prolonged exposures to anticonvulsant drugs

Barbiturates and benzodiazepines are potent GABA(A) receptor agonists and strong anticonvulsants. In the developing brain they can cause neuronal and oligodendroglia apoptosis, impair synaptogenesis, inhibit neurogenesis and trigger long-term neurocognitive sequelae. In humans, the vulnerable period...

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發表在:Neurobiol Dis
Main Authors: Noguchi, Kevin K., Fuhler, Nicole A., Wang, Sophie H., Capuano, Saverio, Brunner, Kevin R., Larson, Shreya, Crosno, Kristin, Simmons, Heather A., Mejia, Andres F., Martin, Lauren D., Dissen, Gregory A., Brambrink, Ansgar, Ikonomidou, Chrysanthy
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856070/
https://ncbi.nlm.nih.gov/pubmed/33385515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105245
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