Brain pathology caused in the neonatal macaque by short and prolonged exposures to anticonvulsant drugs

Barbiturates and benzodiazepines are potent GABA(A) receptor agonists and strong anticonvulsants. In the developing brain they can cause neuronal and oligodendroglia apoptosis, impair synaptogenesis, inhibit neurogenesis and trigger long-term neurocognitive sequelae. In humans, the vulnerable period...

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Bibliografske podrobnosti
izdano v:Neurobiol Dis
Main Authors: Noguchi, Kevin K., Fuhler, Nicole A., Wang, Sophie H., Capuano, Saverio, Brunner, Kevin R., Larson, Shreya, Crosno, Kristin, Simmons, Heather A., Mejia, Andres F., Martin, Lauren D., Dissen, Gregory A., Brambrink, Ansgar, Ikonomidou, Chrysanthy
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7856070/
https://ncbi.nlm.nih.gov/pubmed/33385515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2020.105245
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