Isoflurane exposure leads to apoptosis of neurons and oligodendrocytes in 20- and 40-day old rhesus macaques

Previously we reported that a 5-hour exposure of 6-day-old (P6) rhesus macaques to isoflurane triggers robust neuron and oligodendrocyte apoptosis. In an attempt to further describe the window of vulnerability to anesthetic neurotoxicity, we exposed P20 and P40 rhesusmacaques to 5 h of isoflurane an...

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Publicado en:Neurotoxicol Teratol
Main Authors: Schenning, Katie J., Noguchi, Kevin K., Martin, Lauren Drew, Manzella, Francesca M., Cabrera, Omar H., Dissen, Gregory A, Brambrink, Ansgar M.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5367949/
https://ncbi.nlm.nih.gov/pubmed/27876652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ntt.2016.11.006
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