A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow‐Fed Young Adult Mice

Oxidized phospholipids containing phosphocholine (OxPL) are pro‐inflammatory lipid peroxidation products that bind to scavenger receptors (SRs), such as Scarb1, and toll‐like receptors (TLRs). Excessive OxPL, as found in oxidized low‐density lipoprotein (OxLDL), overwhelm these defense mechanisms an...

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Bibliografische gegevens
Gepubliceerd in:J Bone Miner Res
Hoofdauteurs: Palmieri, Michela, Kim, Ha‐Neui, Gomez‐Acevedo, Horacio, Que, Xuchu, Tsimikas, Sotirios, Jilka, Robert L, Manolagas, Stavros C, Witztum, Joseph L, Ambrogini, Elena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley & Sons, Inc. 2020
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855899/
https://ncbi.nlm.nih.gov/pubmed/32990984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.4173
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