A Neutralizing Antibody Targeting Oxidized Phospholipids Promotes Bone Anabolism in Chow‐Fed Young Adult Mice

Oxidized phospholipids containing phosphocholine (OxPL) are pro‐inflammatory lipid peroxidation products that bind to scavenger receptors (SRs), such as Scarb1, and toll‐like receptors (TLRs). Excessive OxPL, as found in oxidized low‐density lipoprotein (OxLDL), overwhelm these defense mechanisms an...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Palmieri, Michela, Kim, Ha‐Neui, Gomez‐Acevedo, Horacio, Que, Xuchu, Tsimikas, Sotirios, Jilka, Robert L, Manolagas, Stavros C, Witztum, Joseph L, Ambrogini, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855899/
https://ncbi.nlm.nih.gov/pubmed/32990984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.4173
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