Dose- and time-dependent increase in circulating anti-inflammatory and pro-resolving lipid mediators following eicosapentaenoic acid supplementation in patients with major depressive disorder and chronic inflammation

BACKGROUND: Eicosapentaenoic acid (EPA) supplementation is an effective treatment option in major depressive disorder (MDD) associated with chronic low-grade inflammation. EPA is the precursor of specialized pro-resolving lipid mediators (SPMs) termed resolvins (Rv), that serve important roles in th...

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Published in:Prostaglandins Leukot Essent Fatty Acids
Main Authors: Lamon-Fava, Stefania, So, Jisun, Mischoulon, David, Ziegler, Thomas R., Dunlop, Boadie W., Kinkead, Becky, Schettler, Pamela J., Nierenberg, Andrew A., Felger, Jennifer C., Maddipati, Krishna Rao, Fava, Maurizio, Rapaport, Mark Hyman
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855824/
https://ncbi.nlm.nih.gov/pubmed/33316626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plefa.2020.102219
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