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GATA4 Regulates Mesenchymal Stem Cells via Direct Transcriptional Regulation of the WNT Signalosome
GATA4 is a transcription factor that regulates osteoblast differentiation. However, GATA4 is expressed at a higher level in mesenchymal stem cells (MSCs) than in osteoblasts. Therefore, the role of GATA4 in limb bud mesenchyme differentiation was investigated in mice by knocking out Gata4 using Cre-...
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| Veröffentlicht in: | Bone |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7855755/ https://ncbi.nlm.nih.gov/pubmed/33338666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2020.115819 |
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