GATA4 Regulates Estrogen Receptor-α-Mediated Osteoblast Transcription

Estrogens regulate osteoblast differentiation and mineralization. We identified GATA4 as a transcription factor expressed in osteoblasts and directly regulated by 17β-estradiol in this cell type but not in breast cancer cells, another estrogen-responsive tissue. Chromatin immunoprecipitation sequenc...

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Autori principali: Miranda-Carboni, Gustavo A., Guemes, Miriam, Bailey, Shannon, Anaya, Edgar, Corselli, Mirko, Peault, Bruno, Krum, Susan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2011
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3125091/
https://ncbi.nlm.nih.gov/pubmed/21566084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0463
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