Creatinine-Based Renal Function Assessment in Pediatric Drug Development: An Analysis Using Clinical Data for Renally Eliminated Drugs

The estimated glomerular filtration rate (eGFR) equations based on serum creatinine (SCR) have been used for pediatric dose adjustment in drug labeling. This study evaluated the performance of those equations in estimating individual clearance of drugs that are predominantly eliminated by glomerular...

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Vydáno v:Clin Pharmacol Ther
Hlavní autoři: Zhang, Yifei, Sherwin, Catherine M., Gonzalez, Daniel, Zhang, Qunshu, Khurana, Mona, Fisher, Jeffrey, Burckart, Gilbert J., Wang, Yaning, Yao, Lynne P., Ganley, Charles J., Wang, Jian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855729/
https://ncbi.nlm.nih.gov/pubmed/32696977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1991
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