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Using genetically encoded heme sensors to probe the mechanisms of heme uptake and homeostasis in Candida albicans

Candida albicans is a major fungal pathogen that can utilize hemin and hemoglobin as iron sources in the iron-scarce host environment. While C. albicans is a heme prototroph, we show here that it can also efficiently utilize external heme as a cellular heme source. Using genetically encoded ratiomet...

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Vydáno v:Cell Microbiol
Hlavní autoři: Weissman, Ziva, Pinsky, Mariel, Donegan, Rebecca K., Reddi, Amit R., Kornitzer, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855654/
https://ncbi.nlm.nih.gov/pubmed/33104284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.13282
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