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“SLAMF7 signaling reprograms T cells towards exhaustion in the tumor microenvironment.”

T cell exhaustion represents one of the most pervasive strategies tumors employ to circumvent the immune system. While repetitive, cognate T cell receptor signaling is recognized as the primary driving force behind this phenomenon, it remains unknown what other forces drive T cell exhaustion in the...

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Dettagli Bibliografici
Pubblicato in:J Immunol
Autori principali: O’Connell, Patrick, Hyslop, Sean, Blake, Maja K., Godbehere, Sarah, Amalfitano, Andrea, Aldhamen, Yasser A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855551/
https://ncbi.nlm.nih.gov/pubmed/33288545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000300
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