Phosphatase of Regenerating Liver-1 selectively times circadian behavior in darkness via function in PDF neurons and dephosphorylation of TIMELESS

The timing of behavior under natural light-dark conditions is a function of circadian clocks and photic input pathways. Yet a mechanistic understanding of how these pathways collaborate in animals is lacking. Here we demonstrate in Drosophila that the Phosphatase of Regenerating Liver-1 (PRL-1) sets...

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Pubblicato in:Curr Biol
Autori principali: Kula-Eversole, Elżbieta, Lee, Da Hyun, Samba, Ima, Yildirim, Evrim, Levine, Daniel C., Hong, Hee-Kyung, Lear, Bridget C., Bass, Joseph, Rosbash, Michael, Allada, Ravi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855481/
https://ncbi.nlm.nih.gov/pubmed/33157022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.10.013
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