Is there a link between inorganic polyphosphate (polyP), mitochondria, and neurodegeneration?

Mitochondrial dysfunction – including increased apoptosis, calcium and protein dyshomeostasis within the organelle, and dysfunctional bioenergetics and oxidative status – is a common and early feature in all the major neurodegenerative diseases, including Alzheimer’s Disease (AD) and Parkinson’s Dis...

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Gepubliceerd in:Pharmacol Res
Hoofdauteurs: Borden, Emily A., Furey, Matthew, Gattone, Nicholas J., Hambardikar, Vedangi D., Liang, Xiao Hua, Scoma, Ernest R., Abou Samra, Antonella, D-Gary, LaKeshia R., Dennis, Dayshaun J., Fricker, Daniel, Garcia, Cindy, Jiang, ZeCheng, Khan, Shariq A., Kumarasamy, Dheenadhayalan, Kuppala, Hasmitha, Ringrose, Savannah, Rosenheim, Evan J., Van Exel, Kimberly, Vudhayagiri, Hemanth Sai, Zhang, Jiarui, Zhang, Zhaowen, Guitart-Mampel, Mariona, Urquiza, Pedro, Solesio, Maria E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855267/
https://ncbi.nlm.nih.gov/pubmed/33010423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2020.105211
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