Is there a link between inorganic polyphosphate (polyP), mitochondria, and neurodegeneration?

Mitochondrial dysfunction – including increased apoptosis, calcium and protein dyshomeostasis within the organelle, and dysfunctional bioenergetics and oxidative status – is a common and early feature in all the major neurodegenerative diseases, including Alzheimer’s Disease (AD) and Parkinson’s Dis...

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Bibliografske podrobnosti
izdano v:Pharmacol Res
Main Authors: Borden, Emily A., Furey, Matthew, Gattone, Nicholas J., Hambardikar, Vedangi D., Liang, Xiao Hua, Scoma, Ernest R., Abou Samra, Antonella, D-Gary, LaKeshia R., Dennis, Dayshaun J., Fricker, Daniel, Garcia, Cindy, Jiang, ZeCheng, Khan, Shariq A., Kumarasamy, Dheenadhayalan, Kuppala, Hasmitha, Ringrose, Savannah, Rosenheim, Evan J., Van Exel, Kimberly, Vudhayagiri, Hemanth Sai, Zhang, Jiarui, Zhang, Zhaowen, Guitart-Mampel, Mariona, Urquiza, Pedro, Solesio, Maria E.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855267/
https://ncbi.nlm.nih.gov/pubmed/33010423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2020.105211
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