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Optogenetic manipulation of an ascending arousal system tunes cortical broadband gamma power and reveals functional deficits relevant to schizophrenia

Increases in broadband cortical electroencephalogram (EEG) power in the gamma band (30–80 Hz) range have been observed in schizophrenia patients and in mouse models of schizophrenia. They are also seen in humans and animals treated with the psychotomimetic agent ketamine. However, the mechanisms whi...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: McNally, James M., Aguilar, David D., Katsuki, Fumi, Radzik, Leana, Schiffino, Felipe L., Uygun, David S., McKenna, James T., Strecker, Robert E., Deisseroth, Karl, Spencer, Kevin M., Brown, Ritchie E., Nat, Rer
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7855059/
https://ncbi.nlm.nih.gov/pubmed/32690865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-020-0840-3
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