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Thalamic Reticular Nucleus Parvalbumin Neurons Regulate Sleep Spindles and Electrophysiological Aspects of Schizophrenia in Mice

The thalamic reticular nucleus (TRN) is implicated in schizophrenia pathology. However, it remains unclear whether alterations of TRN activity can account for abnormal electroencephalographic activity observed in patients, namely reduced spindles (10–15 Hz) during sleep and increased delta (0.5–4 Hz...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Thankachan, Stephen, Katsuki, Fumi, McKenna, James T., Yang, Chun, Shukla, Charu, Deisseroth, Karl, Uygun, David S., Strecker, Robert E., Brown, Ritchie E., McNally, James M., Basheer, Radhika
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401113/
https://ncbi.nlm.nih.gov/pubmed/30837664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40398-9
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